Why does vitiligo easily appear in exposed areas?

Why does vitiligo easily appear in exposed areas

1. Firstly, the reason why vitiligo is prone to occur in exposed areas is that the exposed parts of the skin are easily stimulated by external stimuli such as mechanical friction, compression, squeezing, etc., which can lead to abnormal melanin metabolism and make vitiligo prone to occur. The reason why stimulated areas can cause vitiligo is that the friction area is prone to trauma, which can lead to changes in neural structure and function, which may increase the synthesis of neurotransmitters, consume too much tyrosine, reduce melanin synthesis, and make vitiligo prone to occur.

2. It is also closely related to daily exposure to sunlight. Moderate exposure to sunlight is beneficial for the human body, but it can cause the hyperfunction of melanocytes, promote their consumption, affect melanin synthesis, and easily lead to the onset of vitiligo.

3. Frequent exposure to chemicals is also one of the important reasons why exposed skin is prone to white spots. The chemical substances that often cause the onset of vitiligo, among which the most obvious are phenolic compounds such as catechol, hydroquinone, p-tert-butyl phenol, phenol, butyl phenol, butyl acid, etc., because these substances have a destructive effect on melanin, causing pigment loss and making vitiligo prone to occur.